Use of male mice skews drug research against women, study finds

Use of male mice skews drug research against women, study finds

The male bias is seen across all fields of pre-clinical research, but one of the starkest areas is neuroscience, in which male animals outnumber females by nearly six to one. Recent research has challenged the reasoning behind using almost exclusively male animals, with one analysis of nearly 300 neuroscience studies revealing that data collected from female mice was not more variable than that from males – in fact, for some measures, the reverse was true. She is also concerned about the approach taken by some research teams in the US which incorporate both sexes in experiments by working things out in males first and then repeating it in females.

Source: www.theguardian.com