Ketamine: From Party Drug to Prescription Medicine
Others argue that esketamine has the potential to help individuals whose depression is debilitating and unresponsive to other treatments. In the 1990s, the scientist Phil Skolnick realized that the drug could lessen depressive symptoms, and in 2000, a team of scientists at Yale University found that doses of ketamine provided quick relief to seven people with depression. To date, findings indicate that patients given esketamine report significant reductions in depression symptoms even up to two weeks after treatment.
Source: www.cugmhp.org